Cannabinoid

A class of chemical compounds that occur naturally in the cannabis plant (“phytocannabinoids,” like THC and CBD) and are also produced in the human body (“endocannabinoids,” like anandamide). Consumers report that these compounds help regulate processes like mood, pain sensation, appetite, and memory.

Whether plant-derived or synthetically produced, all cannabinoids exert their purported effects by binding to cannabinoid receptors in the human body and altering neurotransmitter signaling. In short, they hijack the brain’s own chill-out system and tweak the dials just enough to make you feel something—or, if you really go hard, nothing at all.

Over 100 naturally occuring (‘phyto’) cannabinoids have been identified in cannabis​ (but don’t worry, law enforcement is furiously searching for more). The most notable are:

• Delta 9 THC (tetrahydrocannabinol), which causes the characteristic “high” by activating CB1 receptors in the brain
• CBD (cannabidiol)—THC’s responsible older brother, who’s non-intoxicating, can modulate the effects of THC, and provide therapeutic benefits​​

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