Bioavailability

In pharmacology, bioavailability refers to how much THC is absorbed into the bloodstream and made available at the site of biological activity.

In English?

It’s the percentage of a consumed THC dose that actively affects your body. (If that percentage is zero, buddy, you just bought oregano.)

For example:

  • Smoking or vaping THC delivers cannabinoids to the bloodstream rapidly (high bioavailability—like… so high)
  • Ingesting THC, tastefully named edibles, delays and often reduces the bioavailability because your body must first digest it and metabolize it in your liver (but it usually also comes with a marked decrease in coughing fits)


In short, optimizing bioavailability is important because it determines the effective potency of your dose of THC.

Cannabis flower and joints artfully arranged on a table

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